Among the ameloblastomas, the desmoplastic variation is rare. The desmoplastic ameloblastoma (DA) is characterized by specific clinical, imaging, and. Desmoplastic ameloblastoma (DA) is a rare variant of ameloblastoma, and less than patients have been reported in the literature. The present case. Desmoplastic Ameloblastoma is a rare variant of ameloblastoma. 90 cases of desmoplastic ameloblastoma have been reported so far in literature. We are.

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They speculated that secondary desmoplastic changes occur in the stroma of conventional ameloblastoma or areas of primary DA desmopalstic into a conventional ameloblastoma.

A painless swelling or bony expansion are the most conspicuous clinical manifestation in most cases [ 2 — 5 ].

Desmoplastic ameloblastoma with osteoplasia: Review of literature with a case report

The cut surface was solid and whitish in most cases. Desmoplastic ameloblastoma DA is one amdloblastoma the 6 histopathological subtypes of ameloblastoma. Desmoplastic variant of ameloblastoma in Chinese patients. Panoramic view showing right nasal floor involvement Click here to view.

Usually asymptomatic and can be found incidentally on routine dental examinations Can also present as a painless swelling or expansion of jaw Pain and paresthesia are uncommon Slow growing, rarely metastasizes to lungs or CNS Metastases associated with tumor of long duration, multiple surgical procedures, radiation therapy Associated with nevoid basal cell carcinoma Gorlin syndrome Fam Cancer ameloblastoms Data from different geographical regions seem to suggest a biogeographical pattern in that the relative frequency of desmoplastic ameloblastoma is slightly higher in Asian population.

The lesion caused divergence of the root of the lateral incisor, without any drsmoplastic of root resorption Figure 2.


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Clinicopathological characteristics of desmoplastic ameloblastoma: As this may have a fibrotic stroma, the squamous metaplasia observed in some areas of the desmoplastic variant of ameloblastoma may mimic it if the palisading layer of the tall columnar cells is not identified. A provisional diagnosis of benign fibro-osseous lesion was made and an incisional biopsy was done.

Desmoplastic variant of ameloblastoma tends to infiltrate between bone trabeculae. Advanced Search Users Online: Matsuo A, Ueno S. In all the reported cases of desmoplastic ameloblastomas, typical radiographic features of ameloblastoma were not observed. Immunohistochemically, expressions of extracellular matrix proteins, tenascin, fibronectin, and type I collagen, in a hybrid ameloblastoma lesion, have been reported suggesting that these extracellular matrix proteins participate in tumoral modulation in hybrid lesions [ 15 ].

For proper understanding of such cases, more in depth analysis and long term follow up is required. The importance lies in the differences in the clinical behavior and management of these two tumors.

Brazilian Journal of Oral Sciences.

Follicular pattern low power. Articles from Journal of Oral and Maxillofacial Pathology: Immunohistochemical demonstration of keratin in ameloblastoma as an indication of tumor differentiation.

Ameloblastoma is a potentially aggressive tumor that requires en bloc resection. None, Conflict of Interest: Intraoral periapical radiograph shows an ill-defined multilocular lesion with loss of periodontal ligament space and displacement of lateral incisor a ; maxillary occlusal radiograph showing multilocular appearance and buccal cortical expansion b.

Case of the Week Grade I mobility of ameloblstoma and 22 was also noticed. The definite diagnosis requires histopathological examination. Report of a case and review of the literature. The mucosa over the swelling appeared normal.


Surgical pathology of the head and neck. The extracellular matrix has an important role in the behavior of neoplastic cells and immunohistochemical studies on the expression of tenascin and fibronectin proteins and Type I collagen in hybrid lesions have also been reported. Therefore, it is necessary to include these in the differential diagnosis. Approximately half of the desmoplastic lesions are located in the maxilla, and the vast majority of them occur in the anterior or premolar portion of the jaws.

Archives of Iranian Medicine. Case Reports in Pathology. We are presenting a rare case of desmoplastic ameloblastoma in the ramus region of mandible with regards to its clinical and radiographical viewpoints.

However curettage leaves islands of tumor within bone, which later manifest as recurrences. Computed tomography of the lesion showed a predominantly desmolastic expansile multiloculated desmoplatsic, with a size of 3.

Effiom OA, Odukoya O. Odontogenic Tumors and Allied Lesions. Journal International Medical Sciences Academy. The risk of recurrence is high. Hence it can be suggested that if the desmoplasia is caused by tumor cell stimulation of stromal fibroblasts, then that stimuli could also affect another cell type, i.

Keratin immunoreactivity is confined to the tumor cells showing squamous differentiation. This article has been cited by other articles in PMC.

Desmoplastic ameloblastoma

Immunoexpression of transforming growth factor beta in desmoplastic ameloblastoma. Radiographically, desmoplastic ameloblastoma usually appears as a mixed radiolucent and radiopaque lesion sometimes mimicking a benign fibro-osseous lesion. Again, the borders of DA are usually poorly defined.