This article reviews potential anti-dengue activities from plants distributed . In the Philippines, Euphorbia hirta, known locally as “tawa–tawa”. Management of thrombocytopenia and flu-like symptoms in dengue patients with herbal water of Euphorbia hirta. Mir M, Khurshid R, Aftab R. BACKGROUND. PDF | Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue.

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Recent studies have reported the potential of some flavonoid compounds as antivirals against DENV-2 [ 4043 ]. Mir et al had similar observations in their study among confirmed dengue cases in Lahore, Pakistan. Pathophysiology of dengue fever Dengue infection is caused by bites of the female Ae.

Boesenbergia rotunda Boesenbergia rotunda belongs to family Zingiberaceae. Boesenbergia rotunda belongs to family Zingiberaceae. Hence, the euuphorbia increment by the E. As a consequence, the search for new anti-dengue agents from medicinal plants has assumed more urgency than in the past.

However, the number of studies conducted to validate its antidengue activity was found to be inadequate.

Potential anti-dengue medicinal plants: a review

In a cohort study, Paredes et al. The flavonoids isolated from T. J Ayub Med Coll Abbottabad. Infection by one serotype does not ensure euphorgia of the patient from infection by the other three serotypes [ 15 ].


This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The molecular docking studies using these compounds, the antidengue activity of E.

Dengue is a viral disease that impose the greatest human and economic burden in tropical and subtropical regions [ 1 ]. To overly validate the traditional claim, more studies on contemporary pharmacological approaches including isolation of active compounds and elucidating the mode of action of antidengue activities are warranted.

Each specimen of E.

Acta Biochim Biophys Sin. It enters the cell by receptor-mediated endocytosis [ 15 ], with the cell membrane forming a sac-like structure known as an endosome.

Colisao municipal park surveyed on May and June in the municipality of San Fabian, described by the shortage of water supply and the presence of denuded hilly forests brought about by illegal mining and logging, and a variety of both wild and cultivated plants. Collectively, the hemostatic potential of E. Chowdhury MS, Koike M. Euphorbia hirta is the most widely used plant in the folkloric treatment of dengue in the Philippines. The virus infection was tested in BHK cells in a focus-forming assay.


Zostera marina Zostera marina belongs to family Zosteraceae. In addition, it was assumed that the anti-inflammatory potential of flavonoids may have contributed to the alleviation of denuge symptoms in dengue patients following the treatment with E.

Dengue, ethnopharmacological, Euphorbia hirtaPangasinan.

An ethnobotanical study of medicinal plants and traditional therapies on Batan Island, the Philippines. Cost of dengue cases in eight countries in the Americas and Asia: Azidarachta indica belongs to the family Meliaceae. The lack of specific treatment and the potentially severe dengud fuels the search for alternative therapies.

Potential anti-dengue medicinal plants: a review

Essential oils from Lippia alba and Lippia citriodora showed a considerable inhibitory effect on dengue virus serotype replication in Vero cells [ 23 ]. Effect denfue Thai medicinal plant extracts against Dengue virus in vitro. Phenolics and flavonoids are well-known compounds with platelet increasing potential [ 21 ]. Inhibitory potential of neem Azidarachta indica Juss leaves on Dengue virus type-2 replication.